KIF13B-mediated VEGFR2 trafficking is essential for vascular leakage and metastasis in vivo

VEGF-A induces vascular leakage and angiogenesis via activating the cell surface localized receptor VEGF receptor 2 (VEGFR2). The amount of available VEGFR2 at the cell surface is however tightly regulated by trafficking of VEGFR2 by kinesin family 13 B (KIF13B), a plus-end kinesin motor, to the pla...

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Detalles Bibliográficos
Autores principales: Waters, Stephen B, Dominguez, Joseph R, Cho, Hyun-Dong, Sarich, Nicolene A, Malik, Asrar B, Yamada, Kaori H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548263/
https://www.ncbi.nlm.nih.gov/pubmed/34670814
http://dx.doi.org/10.26508/lsa.202101170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548263/
https://www.ncbi.nlm.nih.gov/pubmed/34670814
http://dx.doi.org/10.26508/lsa.202101170

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