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Prostaglandin-E2 receptor-4 stimulant rescues cardiac malfunction during myocarditis and protects the heart from adverse ventricular remodeling after myocarditis

Cardioprotective effect of prostaglandin-E2 receptor-4 (EP4) stimulation on the ischemic heart has been demonstrated. Its effect on the heart affected by myocarditis, however, remains uncertain. In this study, we investigated therapeutic effect of EP4 stimulant using a mouse model of autoimmune myoc...

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Detalles Bibliográficos
Autores principales: Takakuma, Akira, Nishii, Mototsugu, Valaperti, Alan, Hiraga, Haruto, Saji, Ryo, Sakai, Kazuya, Matsumura, Reo, Miyata, Yasuo, Oba, Nozomu, Nunose, Fumiya, Ogawa, Fumihiro, Tamura, Kouichi, Takeuchi, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548292/
https://www.ncbi.nlm.nih.gov/pubmed/34702968
http://dx.doi.org/10.1038/s41598-021-99930-5