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Prostaglandin-E2 receptor-4 stimulant rescues cardiac malfunction during myocarditis and protects the heart from adverse ventricular remodeling after myocarditis
Cardioprotective effect of prostaglandin-E2 receptor-4 (EP4) stimulation on the ischemic heart has been demonstrated. Its effect on the heart affected by myocarditis, however, remains uncertain. In this study, we investigated therapeutic effect of EP4 stimulant using a mouse model of autoimmune myoc...
Autores principales: | Takakuma, Akira, Nishii, Mototsugu, Valaperti, Alan, Hiraga, Haruto, Saji, Ryo, Sakai, Kazuya, Matsumura, Reo, Miyata, Yasuo, Oba, Nozomu, Nunose, Fumiya, Ogawa, Fumihiro, Tamura, Kouichi, Takeuchi, Ichiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548292/ https://www.ncbi.nlm.nih.gov/pubmed/34702968 http://dx.doi.org/10.1038/s41598-021-99930-5 |
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