Novel cytoplasmic lncRNA IKBKBAS promotes lung adenocarcinoma metastasis by upregulating IKKβ and consequential activation of NF-κB signaling pathway

NF-κB signaling pathway is a critical link between inflammation and cancer. Emerging evidence suggested that long non-coding RNAs (lncRNAs) were involved in dysregulation of NF-κB. Herein, we reported a novel lncRNA IKBKBAS that activated NF-κB in lung adenocarcinoma (LUAD) by upregulating IKKβ, a k...

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Detalles Bibliográficos
Autores principales: Xing, Yuanxin, Lin, Yani, Zhang, Ying, Hu, Jing, Liu, Junmei, Tian, Yuanyuan, Zhao, Jian, Chen, Weiwen, Han, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548314/
https://www.ncbi.nlm.nih.gov/pubmed/34702815
http://dx.doi.org/10.1038/s41419-021-04304-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548314/
https://www.ncbi.nlm.nih.gov/pubmed/34702815
http://dx.doi.org/10.1038/s41419-021-04304-4

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