A splicing variant of TFEB negatively regulates the TFEB-autophagy pathway

Transcription factor EB (TFEB) is a master regulator of the autophagy-lysosomal pathway (ALP). Here, we cloned a novel splicing variant of TFEB, comprising 281 amino acids (hereafter referred to as small TFEB), and lacking the helix-loop-helix (HLH) and leucine zipper (LZ) motifs present in the full...

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Detalles Bibliográficos
Autores principales: Park, Jee-Yun, Sohn, Hee-Young, Koh, Young Ho, Jo, Chulman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548335/
https://www.ncbi.nlm.nih.gov/pubmed/34702966
http://dx.doi.org/10.1038/s41598-021-00613-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548335/
https://www.ncbi.nlm.nih.gov/pubmed/34702966
http://dx.doi.org/10.1038/s41598-021-00613-y

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