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Hypothalamic kinin B1 receptor mediates orexin system hyperactivity in neurogenic hypertension

Brain orexin system hyperactivity contributes to neurogenic hypertension. We previously reported upregulated neuronal kinin B1 receptor (B1R) expression in hypertension. However, the role of central B1R activation on the orexin system in neurogenic hypertension has not been examined. We hypothesized...

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Detalles Bibliográficos
Autores principales: Parekh, Rohan Umesh, White, Acacia, Leffler, Korin E., Biancardi, Vinicia C., Eells, Jeffrey B., Abdel-Rahman, Abdel A., Sriramula, Srinivas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548389/
https://www.ncbi.nlm.nih.gov/pubmed/34702886
http://dx.doi.org/10.1038/s41598-021-00522-0