Clonal hematopoiesis with JAK2V617F promotes pulmonary hypertension with ALK1 upregulation in lung neutrophils

Pulmonary hypertension (PH) is a progressive cardiopulmonary disease characterized by pulmonary arterial remodeling. Clonal somatic mutations including JAK2V617F, the most frequent driver mutation among myeloproliferative neoplasms, have recently been identified in healthy individuals without hemato...

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Detalles Bibliográficos
Autores principales: Kimishima, Yusuke, Misaka, Tomofumi, Yokokawa, Tetsuro, Wada, Kento, Ueda, Koki, Sugimoto, Koichi, Minakawa, Keiji, Nakazato, Kazuhiko, Ishida, Takafumi, Oshima, Motohiko, Koide, Shuhei, Shide, Kotaro, Shimoda, Kazuya, Iwama, Atsushi, Ikeda, Kazuhiko, Takeishi, Yasuchika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548396/
https://www.ncbi.nlm.nih.gov/pubmed/34702814
http://dx.doi.org/10.1038/s41467-021-26435-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548396/
https://www.ncbi.nlm.nih.gov/pubmed/34702814
http://dx.doi.org/10.1038/s41467-021-26435-0

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