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The 20S as a stand-alone proteasome in cells can degrade the ubiquitin tag

The proteasome, the primary protease for ubiquitin-dependent proteolysis in eukaryotes, is usually found as a mixture of 30S, 26S, and 20S complexes. These complexes have common catalytic sites, which makes it challenging to determine their distinctive roles in intracellular proteolysis. Here, we ch...

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Detalles Bibliográficos
Autores principales: Sahu, Indrajit, Mali, Sachitanand M., Sulkshane, Prasad, Xu, Cong, Rozenberg, Andrey, Morag, Roni, Sahoo, Manisha Priyadarsini, Singh, Sumeet K., Ding, Zhanyu, Wang, Yifan, Day, Sharleen, Cong, Yao, Kleifeld, Oded, Brik, Ashraf, Glickman, Michael H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548400/
https://www.ncbi.nlm.nih.gov/pubmed/34702852
http://dx.doi.org/10.1038/s41467-021-26427-0