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Cefazolin Improves Anesthesia and Surgery-Induced Cognitive Impairments by Modulating Blood-Brain Barrier Function, Gut Bacteria and Short Chain Fatty Acids

Emerging evidence suggests that anesthesia and surgery may induce gut dysbiosis. Gut dysbiosis leads to imbalance in circulating contents of microbiota-derived metabolites and disrupts the integrity of the blood-brain barrier (BBB), contributing to postoperative cognitive dysfunction (POCD). The com...

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Detalles Bibliográficos
Autores principales: Luo, Ailin, Li, Shan, Wang, Xuan, Xie, Zheng, Li, Shiyong, Hua, Dongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548472/
https://www.ncbi.nlm.nih.gov/pubmed/34720997
http://dx.doi.org/10.3389/fnagi.2021.748637