The impact of physiological metabolite levels on serine uptake, synthesis and utilization in cancer cells

Serine is a non-essential amino acid that is critical for tumour proliferation and depletion of circulating serine results in reduced tumour growth and increased survival in various cancer models. While many cancer cells cultured in a standard tissue culture medium depend on exogenous serine for opt...

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Detalles Bibliográficos
Autores principales: Hennequart, Marc, Labuschagne, Christiaan F., Tajan, Mylène, Pilley, Steven E., Cheung, Eric C., Legrave, Nathalie M., Driscoll, Paul C., Vousden, Karen H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548528/
https://www.ncbi.nlm.nih.gov/pubmed/34702840
http://dx.doi.org/10.1038/s41467-021-26395-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548528/
https://www.ncbi.nlm.nih.gov/pubmed/34702840
http://dx.doi.org/10.1038/s41467-021-26395-5

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