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The impact of physiological metabolite levels on serine uptake, synthesis and utilization in cancer cells
Serine is a non-essential amino acid that is critical for tumour proliferation and depletion of circulating serine results in reduced tumour growth and increased survival in various cancer models. While many cancer cells cultured in a standard tissue culture medium depend on exogenous serine for opt...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548528/ https://www.ncbi.nlm.nih.gov/pubmed/34702840 http://dx.doi.org/10.1038/s41467-021-26395-5 |