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Establishment of high-throughput screening HTRF assay for identification small molecule inhibitors of Skp2-Cks1
S-phase kinase associated protein 2 (Skp2), a member of the F-box family that constitute the largest known class of ubiquitin E3 specificity components, is responsible for recognizing and recruiting cyclin-dependent kinase inhibitor p27 for its ubiquitination in the presence of the small accessory p...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548536/ https://www.ncbi.nlm.nih.gov/pubmed/34702937 http://dx.doi.org/10.1038/s41598-021-00646-3 |