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Establishment of high-throughput screening HTRF assay for identification small molecule inhibitors of Skp2-Cks1

S-phase kinase associated protein 2 (Skp2), a member of the F-box family that constitute the largest known class of ubiquitin E3 specificity components, is responsible for recognizing and recruiting cyclin-dependent kinase inhibitor p27 for its ubiquitination in the presence of the small accessory p...

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Detalles Bibliográficos
Autores principales:	Hu, Kaizhao, Li, Xiao-Jing, Asmamaw, Moges Dessale, Shi, Xiao-Jing, Liu, Hong-Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548536/ https://www.ncbi.nlm.nih.gov/pubmed/34702937 http://dx.doi.org/10.1038/s41598-021-00646-3

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