Optimizing the evaluation of gene-targeted panels for tumor mutational burden estimation

Though whole exome sequencing (WES) is the gold-standard for measuring tumor mutational burden (TMB), the development of gene-targeted panels enables cost-effective TMB estimation. With the growing number of panels in clinical trials, developing a statistical method to effectively evaluate and compa...

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Detalles Bibliográficos
Autores principales: Li, Yawei, Luo, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548549/
https://www.ncbi.nlm.nih.gov/pubmed/34702927
http://dx.doi.org/10.1038/s41598-021-00626-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548549/
https://www.ncbi.nlm.nih.gov/pubmed/34702927
http://dx.doi.org/10.1038/s41598-021-00626-7

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