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Optimizing the evaluation of gene-targeted panels for tumor mutational burden estimation

Though whole exome sequencing (WES) is the gold-standard for measuring tumor mutational burden (TMB), the development of gene-targeted panels enables cost-effective TMB estimation. With the growing number of panels in clinical trials, developing a statistical method to effectively evaluate and compa...

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Detalles Bibliográficos
Autores principales:	Li, Yawei, Luo, Yuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548549/ https://www.ncbi.nlm.nih.gov/pubmed/34702927 http://dx.doi.org/10.1038/s41598-021-00626-7

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