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Diminished Peripheral CD29hi Cytotoxic CD4+ T Cells Are Associated With Deleterious Effects During SIV Infection

Cytotoxic CD4+ T cells (CD4+ CTLs) limit HIV pathogenesis, as evidenced in elite controllers (a subset of individuals who suppress the virus without the need for therapy). CD4+ CTLs have also been shown to kill HIV-infected macrophages. However, little is known about their contribution towards HIV p...

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Detalles Bibliográficos
Autores principales: Olwenyi, Omalla A., Johnson, Samuel D., Pandey, Kabita, Thurman, Michellie, Acharya, Arpan, Buch, Shilpa J., Fox, Howard S., Podany, Anthony T., Fletcher, Courtney V., Byrareddy, Siddappa N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548621/
https://www.ncbi.nlm.nih.gov/pubmed/34721397
http://dx.doi.org/10.3389/fimmu.2021.734871