Cargando…

Diminished Peripheral CD29hi Cytotoxic CD4+ T Cells Are Associated With Deleterious Effects During SIV Infection

Cytotoxic CD4+ T cells (CD4+ CTLs) limit HIV pathogenesis, as evidenced in elite controllers (a subset of individuals who suppress the virus without the need for therapy). CD4+ CTLs have also been shown to kill HIV-infected macrophages. However, little is known about their contribution towards HIV p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Olwenyi, Omalla A., Johnson, Samuel D., Pandey, Kabita, Thurman, Michellie, Acharya, Arpan, Buch, Shilpa J., Fox, Howard S., Podany, Anthony T., Fletcher, Courtney V., Byrareddy, Siddappa N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548621/ https://www.ncbi.nlm.nih.gov/pubmed/34721397 http://dx.doi.org/10.3389/fimmu.2021.734871

Ejemplares similares

Chronic Morphine Administration Differentially Modulates Viral Reservoirs in a Simian Immunodeficiency Virus SIVmac251-Infected Rhesus Macaque Model
por: Acharya, Arpan, et al.
Publicado: (2021)

Mental Health Issues During and After COVID-19 Vaccine Era
por: Pandey, Kabita, et al.
Publicado: (2021)

Systems biology analyses reveal enhanced chronic morphine distortion of gut-brain interrelationships in simian human immunodeficiency virus infected rhesus macaques
por: Olwenyi, Omalla A., et al.
Publicado: (2022)

Early treatment with anti-α(4)β(7) antibody facilitates increased gut macrophage maturity in SIV-infected rhesus macaques
por: Johnson, Samuel D., et al.
Publicado: (2022)

Therapeutic implications of SARS-CoV-2 dysregulation of the gut-brain-lung axis
por: Johnson, Samuel D, et al.
Publicado: (2021)

Immuno-epidemiology and pathophysiology of coronavirus disease 2019 (COVID-19)
por: Olwenyi, Omalla A., et al.
Publicado: (2020)

Retinoic Acid Improves the Recovery of Replication-Competent Virus from Latent SIV Infected Cells
por: Olwenyi, Omalla A., et al.
Publicado: (2020)

Peptide Nanoarray Scaffold Vaccine for SARS-COV-2 and Its Variants of Concerns
por: Zagorski, Karen, et al.
Publicado: (2022)

Discovery and Evaluation of Entry Inhibitors for SARS-CoV-2 and Its Emerging Variants
por: Acharya, Arpan, et al.
Publicado: (2021)

Biomarkers of Activation and Inflammation to Track Disparity in Chronological and Physiological Age of People Living With HIV on Combination Antiretroviral Therapy
por: Thurman, Michellie, et al.
Publicado: (2020)

Modular nanoarray vaccine for SARS-CoV-2
por: Zagorski, Karen, et al.
Publicado: (2022)

PI3K‐α/mTOR/BRD4 inhibitor alone or in combination with other anti‐virals blocks replication of SARS‐CoV‐2 and its variants of concern including Delta and Omicron
por: Acharya, Arpan, et al.
Publicado: (2022)

In-vitro Immunomodulatory activity of Azadirachta indica A.Juss. Ethanol: water mixture against HIV associated chronic CD4(+) T-cell activation/ exhaustion
por: Olwenyi, Omalla A., et al.
Publicado: (2021)

Proteomic landscape of astrocytes and pericytes infected with HIV/SARS-CoV-2 mono/co-infection, impacting on neurological complications
por: Acharya, Arpan, et al.
Publicado: (2023)

Antiretroviral therapy restores the homeostatic state of microglia in SIV‐infected rhesus macaques
por: Trease, Andrew J., et al.
Publicado: (2022)

Morphine suppresses peripheral responses and transforms brain myeloid gene expression to favor neuropathogenesis in SIV infection
por: Fox, Howard S., et al.
Publicado: (2022)

miR-15a and miR-15b modulate natural killer and CD8(+)T-cell activation and anti-tumor immune response by targeting PD-L1 in neuroblastoma
por: Pathania, Anup S., et al.
Publicado: (2022)

ACE-2, TMPRSS2, and Neuropilin-1 Receptor Expression on Human Brain Astrocytes and Pericytes and SARS-CoV-2 Infection Kinetics
por: Malik, Johid Reza, et al.
Publicado: (2023)

Preliminary Studies on Immune Response and Viral Pathogenesis of Zika Virus in Rhesus Macaques
por: Woollard, Shawna M., et al.
Publicado: (2018)

Combining antiviral drugs with BET inhibitors is beneficial in combatting SARS‐CoV‐2 infection
por: Acharya, Arpan, et al.
Publicado: (2022)

Impact of Social Determinants of Health on the Emerging COVID-19 Pandemic in the United States
por: Singu, Sravani, et al.
Publicado: (2020)

Responses of CD27(+)CD38(+) plasmablasts, and CD24(hi)CD27(hi) and CD24(hi)CD38(hi) regulatory B cells during primary dengue virus 2 infection
por: Lei, Chenshuang, et al.
Publicado: (2021)

The 2022 outbreak and the pathobiology of the monkeypox virus
por: Kumar, Narendra, et al.
Publicado: (2022)

NF-κB Duplications in the Promoter-Variant HIV-1C LTR Impact Inflammation Without Altering Viral Replication in the Context of Simian Human Immunodeficiency Viruses and Opioid-Exposure
por: Dave, Rajnish S., et al.
Publicado: (2020)

Phenotypic and Functional Characterization of Monoclonal Antibodies with Specificity for Rhesus Macaque CD200, CD200R and Mincle
por: Byrareddy, Siddappa N., et al.
Publicado: (2015)

SARS-CoV-2 Infection Leads to Neurological Dysfunction
por: Acharya, Arpan, et al.
Publicado: (2020)

Loss and regain of SIV control upon CD8+ cell depletion in vivo in SIV-controller macaques is not associated with efficient SIV specific CD8+ T-cells
por: Hamimi, C, et al.
Publicado: (2012)

CD19(+)CD24(hi)CD38(hi) B Cell Dysfunction in Primary Biliary Cholangitis
por: Chen, Qubo, et al.
Publicado: (2020)

Early Treatment of SIV+ macaques with an α(4)β(7) mAb alters virus distribution and preserves CD4(+) T cells in later stages of infection
por: Santangelo, Philip J., et al.
Publicado: (2017)

Deficit of circulating CD19(+)CD24(hi)CD38(hi) regulatory B cells in severe aplastic anaemia
por: Zaimoku, Yoshitaka, et al.
Publicado: (2020)

Correlation of CD19(+)CD24(hi)CD38(hi) B cells in coronary artery disease with severity of atherosclerosis
por: Liu, Yang, et al.
Publicado: (2020)

Molecular Aspects of COVID-19 Differential Pathogenesis
por: Rothan, Hussin A., et al.
Publicado: (2020)

Differential Function of a Novel Population of the CD19+CD24hiCD38hi Bregs in Psoriasis and Multiple Myeloma
por: Bartosińska, Joanna, et al.
Publicado: (2021)

Therapeutic Potential of Cannabis: A Comprehensive Review of Current and Future Applications
por: Leinen, Zach J., et al.
Publicado: (2023)

The role of CD101-expressing CD4 T cells in HIV/SIV pathogenesis and persistence
por: Strongin, Zachary, et al.
Publicado: (2022)

CD27(hi)CD38(hi) plasmablasts are activated B cells of mixed origin with distinct function
por: Rouers, Angeline, et al.
Publicado: (2021)

Immunomodulatory LncRNA on antisense strand of ICAM-1 augments SARS-CoV-2 infection-associated airway mucoinflammatory phenotype
por: Devadoss, Dinesh, et al.
Publicado: (2022)

Low levels of SIV-specific CD8+ T cells in germinal centers characterizes acute SIV infection
por: Li, Shengbin, et al.
Publicado: (2019)

CD19(+)CD24(hi)CD38(hi)Bregs involved in downregulate helper T cells and upregulate regulatory T cells in gastric cancer
por: Wang, Weiwei, et al.
Publicado: (2015)

CD19(+)CD24(hi)CD38(hi) regulatory B cells deficiency revealed severity and poor prognosis in patients with sepsis
por: Wang, Chunmei, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_pfgvg2n003hbp1lnijsl47h6mk