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Defining the Role of Nuclear Factor (NF)-κB p105 Subunit in Human Macrophage by Transcriptomic Analysis of NFKB1 Knockout THP1 Cells

Since its discovery over 30 years ago the NF-ĸB family of transcription factors has gained the status of master regulator of the immune response. Much of what we understand of the role of NF-ĸB in immune development, homeostasis and inflammation comes from studies of mice null for specific NF-ĸB sub...

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Detalles Bibliográficos
Autores principales: Somma, Domenico, Kok, Fatma O., Kerrigan, David, Wells, Christine A., Carmody, Ruaidhrí J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548695/
https://www.ncbi.nlm.nih.gov/pubmed/34721373
http://dx.doi.org/10.3389/fimmu.2021.669906