Cargando…
Defining the Role of Nuclear Factor (NF)-κB p105 Subunit in Human Macrophage by Transcriptomic Analysis of NFKB1 Knockout THP1 Cells
Since its discovery over 30 years ago the NF-ĸB family of transcription factors has gained the status of master regulator of the immune response. Much of what we understand of the role of NF-ĸB in immune development, homeostasis and inflammation comes from studies of mice null for specific NF-ĸB sub...
Autores principales: | Somma, Domenico, Kok, Fatma O., Kerrigan, David, Wells, Christine A., Carmody, Ruaidhrí J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548695/ https://www.ncbi.nlm.nih.gov/pubmed/34721373 http://dx.doi.org/10.3389/fimmu.2021.669906 |
Ejemplares similares
-
The Regulation of NF-κB Subunits by Phosphorylation
por: Christian, Frank, et al.
Publicado: (2016) -
The Ubiquitination of NF-κB Subunits in the Control of Transcription
por: Collins, Patricia E., et al.
Publicado: (2016) -
Defining the structure of the NF-ĸB pathway in human immune cells using quantitative proteomic data
por: Kok, Fatma O., et al.
Publicado: (2021) -
The regulation of sequence specific NF-κB DNA binding and transcription by IKKβ phosphorylation of NF-κB p50 at serine 80
por: Smith, Emma L, et al.
Publicado: (2019) -
The deubiquitinase USP7 uses a distinct ubiquitin-like domain to deubiquitinate NF-ĸB subunits
por: Mitxitorena, Izaskun, et al.
Publicado: (2020)