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Selective Surface and Intraluminal Localization of Wnt Ligands on Small Extracellular Vesicles Released by HT-22 Hippocampal Neurons

The Wnt signaling pathway induces various responses underlying the development and maturation of the nervous system. Wnt ligands are highly hydrophobic proteins that limit their diffusion through an aqueous extracellular medium to a target cell. Nevertheless, their attachment to small extracellular...

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Detalles Bibliográficos
Autores principales: Torres, Viviana I., Barrera, Daniela P., Varas-Godoy, Manuel, Arancibia, Duxan, Inestrosa, Nibaldo C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548728/
https://www.ncbi.nlm.nih.gov/pubmed/34722516
http://dx.doi.org/10.3389/fcell.2021.735888