Non-Ablative Chemotherapy Followed by HLA-Mismatched Allogeneic CD3(+) T-Cells Infusion Causes An Augment of T-Cells With Mild CRS: A Multi-Centers Single-Arm Prospective Study on Elderly Acute Myeloid Leukemia and int-2/High Risk Myelodysplastic Syndrome Patients

OBJECTIVE: To evaluate the efficacy and safety of standard or low-dose chemotherapy followed by HLA-mismatched allogeneic T-cell infusion (allo-TLI) for the treatment of elderly patients with acute myeloid leukemia (AML) and patients with intermediate-2 to high-risk myelodysplastic syndrome (MDS). M...

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Detalles Bibliográficos
Autores principales: Huang, Yan, Hong, Minghua, Qu, Zhigang, Zheng, Weiyan, Hu, Huixian, Li, Linjie, Lu, Ting, Xie, Ying, Ying, Shuangwei, Zhu, Yuanyuan, Liu, Lizhen, Huang, Weijia, Fu, Shan, Chen, Jin, Wu, Kangli, Liu, Mingsuo, Luo, Qiulian, Wu, Yajun, He, Fang, Zhang, Jingcheng, Zhang, Junyu, Chen, Yu, Zhao, Minlei, Cai, Zhen, Huang, He, Sun, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548743/
https://www.ncbi.nlm.nih.gov/pubmed/34722293
http://dx.doi.org/10.3389/fonc.2021.741341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548743/
https://www.ncbi.nlm.nih.gov/pubmed/34722293
http://dx.doi.org/10.3389/fonc.2021.741341

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