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Autophagy Regulates the Survival of Hair Cells and Spiral Ganglion Neurons in Cases of Noise, Ototoxic Drug, and Age-Induced Sensorineural Hearing Loss

Inner ear hair cells (HCs) and spiral ganglion neurons (SGNs) are the core components of the auditory system. However, they are vulnerable to genetic defects, noise exposure, ototoxic drugs and aging, and loss or damage of HCs and SGNs results in permanent hearing loss due to their limited capacity...

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Detalles Bibliográficos
Autores principales: Guo, Lingna, Cao, Wei, Niu, Yuguang, He, Shuangba, Chai, Renjie, Yang, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548757/
https://www.ncbi.nlm.nih.gov/pubmed/34720884
http://dx.doi.org/10.3389/fncel.2021.760422