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Piezo1–Pannexin1 complex couples force detection to ATP secretion in cholangiocytes

Cholangiocytes actively contribute to the final composition of secreted bile. These cells are exposed to abnormal mechanical stimuli during obstructive cholestasis, which has a deep impact on their function. However, the effects of mechanical insults on cholangiocyte function are not understood. Com...

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Detalles Bibliográficos
Autores principales: Desplat, Angélique, Penalba, Virginie, Gros, Emeline, Parpaite, Thibaud, Coste, Bertrand, Delmas, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548913/
https://www.ncbi.nlm.nih.gov/pubmed/34694360
http://dx.doi.org/10.1085/jgp.202112871