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Double‐edged effects of tamoxifen‐in‐oil‐gavage on an infectious murine model for multiple sclerosis

Tamoxifen gavage is a commonly used method to induce genetic modifications in cre‐loxP systems. As a selective estrogen receptor modulator (SERM), the compound is known to have immunomodulatory and neuroprotective properties in non‐infectious central nervous system (CNS) disorders. It can even cause...

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Detalles Bibliográficos
Autores principales: Hülskötter, Kirsten, Jin, Wen, Allnoch, Lisa, Hansmann, Florian, Schmidtke, Daniel, Rohn, Karl, Flügel, Alexander, Lühder, Fred, Baumgärtner, Wolfgang, Herder, Vanessa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549030/
https://www.ncbi.nlm.nih.gov/pubmed/34137105
http://dx.doi.org/10.1111/bpa.12994