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Synthetic Glycomacromolecules of Defined Valency, Absolute Configuration, and Topology Distinguish between Human Lectins

[Image: see text] Carbohydrate-binding proteins (lectins) play vital roles in cell recognition and signaling, including pathogen binding and innate immunity. Thus, targeting lectins, especially those on the surface of immune cells, could advance immunology and drug discovery. Lectins are typically o...

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Detalles Bibliográficos
Autores principales: Hartweg, Manuel, Jiang, Yivan, Yilmaz, Gokhan, Jarvis, Cassie M., Nguyen, Hung V.-T., Primo, Gastón A., Monaco, Alessandra, Beyer, Valentin P., Chen, Kathleen K., Mohapatra, Somesh, Axelrod, Simon, Gómez-Bombarelli, Rafael, Kiessling, Laura L., Becer, C. Remzi, Johnson, Jeremiah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549053/
https://www.ncbi.nlm.nih.gov/pubmed/34723265
http://dx.doi.org/10.1021/jacsau.1c00255