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Repeated exposure to sevoflurane in neonatal rats impairs cognition in adulthood via the PKA-CREB-BDNF signaling pathway

Sevoflurane (Sev) anesthesia is widely used in pediatrics due to its low blood-gas partition coefficient and lack of pungency. However, Sev treatment may lead to cognitive dysfunction in later life. The current study administered Sev to neonatal rats to investigate the effects of Sev treatment on co...

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Detalles Bibliográficos
Autores principales: Zhao, Jili, Ren, Jinyu, Liu, Shuang, Gong, Yanan, Meng, Ping, Tan, Haitao, Chen, Yonggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549089/
https://www.ncbi.nlm.nih.gov/pubmed/34721684
http://dx.doi.org/10.3892/etm.2021.10877