Ribonuclease zymogen induces cytotoxicity upon HIV-1 infection

BACKGROUND: Targeting RNA is a promising yet underdeveloped modality for the selective killing of cells infected with HIV-1. The secretory ribonucleases (RNases) found in vertebrates have cytotoxic ribonucleolytic activity that is kept in check by a cytosolic ribonuclease inhibitor protein, RI. METH...

Descripción completa

Detalles Bibliográficos
Autores principales: Windsor, Ian W., Dudley, Dawn M., O’Connor, David H., Raines, Ronald T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549155/
https://www.ncbi.nlm.nih.gov/pubmed/34702287
http://dx.doi.org/10.1186/s12981-021-00399-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549155/
https://www.ncbi.nlm.nih.gov/pubmed/34702287
http://dx.doi.org/10.1186/s12981-021-00399-z

Ejemplares similares