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Ribonuclease zymogen induces cytotoxicity upon HIV-1 infection

BACKGROUND: Targeting RNA is a promising yet underdeveloped modality for the selective killing of cells infected with HIV-1. The secretory ribonucleases (RNases) found in vertebrates have cytotoxic ribonucleolytic activity that is kept in check by a cytosolic ribonuclease inhibitor protein, RI. METH...

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Detalles Bibliográficos
Autores principales:	Windsor, Ian W., Dudley, Dawn M., O’Connor, David H., Raines, Ronald T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549155/ https://www.ncbi.nlm.nih.gov/pubmed/34702287 http://dx.doi.org/10.1186/s12981-021-00399-z

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