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Synergistic effect of combination chemotherapy with praziquantel and DW-3-15 for Schistosoma japonicum in vitro and in vivo

BACKGROUND: Schistosomiasis is a debilitating and neglected tropical disease for which praziquantel (PZQ) remains the first-choice drug for treatment and control of the disease. In our previous studies, we found that the patented compound DW-3-15 (patent no. ZL201110142538.2) displayed significant a...

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Detalles Bibliográficos
Autores principales: Yang, Zi-Yin, Liu, Zi-Hao, Zhang, Ya-Nan, Li, Chen, Liu, Lei, Pu, Wen-Jie, Xie, Shi-Qi, Xu, Jing, Xia, Chao-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549225/
https://www.ncbi.nlm.nih.gov/pubmed/34702326
http://dx.doi.org/10.1186/s13071-021-05065-x