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Multi-dimensional fragmentomic assay for ultrasensitive early detection of colorectal advanced adenoma and adenocarcinoma

Previous studies on liquid biopsy-based early detection of advanced colorectal adenoma (advCRA) or adenocarcinoma (CRC) were limited by low sensitivity. We performed a prospective study to establish an integrated model using fragmentomic profiles of plasma cell-free DNA (cfDNA) for accurately and co...

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Detalles Bibliográficos
Autores principales: Ma, Xiaoji, Chen, Yikuan, Tang, Wanxiangfu, Bao, Hua, Mo, Shaobo, Liu, Rui, Wu, Shuyu, Bao, Hairong, Li, Yaqi, Zhang, Long, Wu, Xue, Cai, Sanjun, Shao, Yang, Liu, Fangqi, Peng, Junjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549237/
https://www.ncbi.nlm.nih.gov/pubmed/34702327
http://dx.doi.org/10.1186/s13045-021-01189-w