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Multi-dimensional fragmentomic assay for ultrasensitive early detection of colorectal advanced adenoma and adenocarcinoma
Previous studies on liquid biopsy-based early detection of advanced colorectal adenoma (advCRA) or adenocarcinoma (CRC) were limited by low sensitivity. We performed a prospective study to establish an integrated model using fragmentomic profiles of plasma cell-free DNA (cfDNA) for accurately and co...
Autores principales: | Ma, Xiaoji, Chen, Yikuan, Tang, Wanxiangfu, Bao, Hua, Mo, Shaobo, Liu, Rui, Wu, Shuyu, Bao, Hairong, Li, Yaqi, Zhang, Long, Wu, Xue, Cai, Sanjun, Shao, Yang, Liu, Fangqi, Peng, Junjie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549237/ https://www.ncbi.nlm.nih.gov/pubmed/34702327 http://dx.doi.org/10.1186/s13045-021-01189-w |
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