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phasebook: haplotype-aware de novo assembly of diploid genomes from long reads
Haplotype-aware diploid genome assembly is crucial in genomics, precision medicine, and many other disciplines. Long-read sequencing technologies have greatly improved genome assembly. However, current long-read assemblers are either reference based, so introduce biases, or fail to capture the haplo...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549298/ https://www.ncbi.nlm.nih.gov/pubmed/34706745 http://dx.doi.org/10.1186/s13059-021-02512-x |