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Multiomics landscape of the autosomal dominant osteopetrosis type II disease-specific induced pluripotent stem cells
BACKGROUND: Autosomal dominant osteopetrosis type II (ADO2) is a genetically and phenotypically metabolic bone disease, caused by osteoclast abnormalities. The pathways dysregulated in ADO2 could lead to the defects in osteoclast formation and function. However, the mechanism remains elusive. MATERI...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549315/ https://www.ncbi.nlm.nih.gov/pubmed/34702373 http://dx.doi.org/10.1186/s41065-021-00204-x |