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Multiomics landscape of the autosomal dominant osteopetrosis type II disease-specific induced pluripotent stem cells

BACKGROUND: Autosomal dominant osteopetrosis type II (ADO2) is a genetically and phenotypically metabolic bone disease, caused by osteoclast abnormalities. The pathways dysregulated in ADO2 could lead to the defects in osteoclast formation and function. However, the mechanism remains elusive. MATERI...

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Detalles Bibliográficos
Autores principales: Li, Chunhong, Shangguan, Yu, Zhu, Peng, Dai, Weier, Tang, Donge, Ou, Minglin, Dai, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549315/
https://www.ncbi.nlm.nih.gov/pubmed/34702373
http://dx.doi.org/10.1186/s41065-021-00204-x

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