ZIP10 drives osteosarcoma proliferation and chemoresistance through ITGA10-mediated activation of the PI3K/AKT pathway

BACKGROUND: The zinc transporters Zrt- and Irt-related protein (ZIP/SLC39) are overexpressed in human tumors and correlate with poor prognosis; however, their contributions to carcinogenesis and chemoresistance in osteosarcoma (OS) remain unclear. METHODS: We collected 64 OS patient tissues with (n ...

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Detalles Bibliográficos
Autores principales: Li, Hongyu, Shen, Xin, Ma, Mengjun, Liu, Wenzhou, Yang, Wen, Wang, Peng, Cai, Zhaopeng, Mi, Rujia, Lu, Yixuan, Zhuang, Jiahao, Jiang, Yuhang, Song, Yihui, Wu, Yanfeng, Shen, Huiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549349/
https://www.ncbi.nlm.nih.gov/pubmed/34706747
http://dx.doi.org/10.1186/s13046-021-02146-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549349/
https://www.ncbi.nlm.nih.gov/pubmed/34706747
http://dx.doi.org/10.1186/s13046-021-02146-8

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