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ZIP10 drives osteosarcoma proliferation and chemoresistance through ITGA10-mediated activation of the PI3K/AKT pathway
BACKGROUND: The zinc transporters Zrt- and Irt-related protein (ZIP/SLC39) are overexpressed in human tumors and correlate with poor prognosis; however, their contributions to carcinogenesis and chemoresistance in osteosarcoma (OS) remain unclear. METHODS: We collected 64 OS patient tissues with (n ...
Autores principales: | Li, Hongyu, Shen, Xin, Ma, Mengjun, Liu, Wenzhou, Yang, Wen, Wang, Peng, Cai, Zhaopeng, Mi, Rujia, Lu, Yixuan, Zhuang, Jiahao, Jiang, Yuhang, Song, Yihui, Wu, Yanfeng, Shen, Huiyong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549349/ https://www.ncbi.nlm.nih.gov/pubmed/34706747 http://dx.doi.org/10.1186/s13046-021-02146-8 |
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