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Generalizable characteristics of false-positive bacterial variant calls

Minimizing false positives is a critical issue when variant calling as no method is without error. It is common practice to post-process a variant-call file (VCF) using hard filter criteria intended to discriminate true-positive (TP) from false-positive (FP) calls. These are applied on the simple pr...

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Detalles Bibliográficos
Autor principal: Bush, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549357/
https://www.ncbi.nlm.nih.gov/pubmed/34346861
http://dx.doi.org/10.1099/mgen.0.000615