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Hypomethylation and downregulation of miR-23b-3p are associated with upregulated PLAU: a diagnostic and prognostic biomarker in head and neck squamous cell carcinoma

BACKGROUND: DNA methylation and miRNA-target genes play an important part in the early development of various tumors and have been studied as tumor biomarkers. Although previous studies have reported a cluster of molecular events (such as aberrant alterations of genomics and epigenetics), little is...

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Detalles Bibliográficos
Autores principales: Huo, Zirong, Li, Xiaoguang, Zhou, Jieyu, Fan, Yuqin, Wang, Zhentao, Zhang, Zhihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549381/
https://www.ncbi.nlm.nih.gov/pubmed/34702271
http://dx.doi.org/10.1186/s12935-021-02251-w