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A synthetic antibiotic class overcoming bacterial multidrug resistance

The dearth of new medicines effective against antibiotic-resistant bacteria presents a growing global public health concern(1). For more than five decades, the search for new antibiotics has relied heavily on the chemical modification of natural products (semisynthesis), a method ill-equipped to com...

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Detalles Bibliográficos
Autores principales: Mitcheltree, Matthew J., Pisipati, Amarnath, Syroegin, Egor A., Silvestre, Katherine J., Klepacki, Dorota, Mason, Jeremy D., Terwilliger, Daniel W., Testolin, Giambattista, Pote, Aditya R., Wu, Kelvin J. Y., Ladley, Richard Porter, Chatman, Kelly, Mankin, Alexander S., Polikanov, Yury S., Myers, Andrew G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549432/
https://www.ncbi.nlm.nih.gov/pubmed/34707295
http://dx.doi.org/10.1038/s41586-021-04045-6