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A synthetic antibiotic class overcoming bacterial multidrug resistance
The dearth of new medicines effective against antibiotic-resistant bacteria presents a growing global public health concern(1). For more than five decades, the search for new antibiotics has relied heavily on the chemical modification of natural products (semisynthesis), a method ill-equipped to com...
Autores principales: | Mitcheltree, Matthew J., Pisipati, Amarnath, Syroegin, Egor A., Silvestre, Katherine J., Klepacki, Dorota, Mason, Jeremy D., Terwilliger, Daniel W., Testolin, Giambattista, Pote, Aditya R., Wu, Kelvin J. Y., Ladley, Richard Porter, Chatman, Kelly, Mankin, Alexander S., Polikanov, Yury S., Myers, Andrew G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549432/ https://www.ncbi.nlm.nih.gov/pubmed/34707295 http://dx.doi.org/10.1038/s41586-021-04045-6 |
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