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Cytoplasmic Tail Truncation of SARS-CoV-2 Spike Protein Enhances Titer of Pseudotyped Vectors but Masks the Effect of the D614G Mutation

The high pathogenicity of SARS-CoV-2 requires it to be handled under biosafety level 3 conditions. Consequently, Spike protein-pseudotyped vectors are a useful tool to study viral entry and its inhibition, with retroviral, lentiviral (LV), and vesicular stomatitis virus (VSV) vectors the most common...

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Detalles Bibliográficos
Autores principales:	Chen, Hsu-Yu, Huang, Chun, Tian, Lu, Huang, Xiaoli, Zhang, Chennan, Llewellyn, George N., Rogers, Geoffrey L., Andresen, Kevin, O’Gorman, Maurice R. G., Chen, Ya-Wen, Cannon, Paula M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Structure and Assembly
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549521/ https://www.ncbi.nlm.nih.gov/pubmed/34495700 http://dx.doi.org/10.1128/JVI.00966-21

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