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Addiction-Associated Genetic Variants Implicate Brain Cell Type- and Region-Specific Cis-Regulatory Elements in Addiction Neurobiology

Recent large genome-wide association studies have identified multiple confident risk loci linked to addiction-associated behavioral traits. Most genetic variants linked to addiction-associated traits lie in noncoding regions of the genome, likely disrupting cis-regulatory element (CRE) function. CRE...

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Detalles Bibliográficos
Autores principales: Srinivasan, Chaitanya, Phan, BaDoi N., Lawler, Alyssa J., Ramamurthy, Easwaran, Kleyman, Michael, Brown, Ashley R., Kaplow, Irene M., Wirthlin, Morgan E., Pfenning, Andreas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549541/
https://www.ncbi.nlm.nih.gov/pubmed/34462306
http://dx.doi.org/10.1523/JNEUROSCI.2534-20.2021