Cargando…

Addiction-Associated Genetic Variants Implicate Brain Cell Type- and Region-Specific Cis-Regulatory Elements in Addiction Neurobiology

Recent large genome-wide association studies have identified multiple confident risk loci linked to addiction-associated behavioral traits. Most genetic variants linked to addiction-associated traits lie in noncoding regions of the genome, likely disrupting cis-regulatory element (CRE) function. CRE...

Descripción completa

Detalles Bibliográficos
Autores principales:	Srinivasan, Chaitanya, Phan, BaDoi N., Lawler, Alyssa J., Ramamurthy, Easwaran, Kleyman, Michael, Brown, Ashley R., Kaplow, Irene M., Wirthlin, Morgan E., Pfenning, Andreas R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Society for Neuroscience 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549541/ https://www.ncbi.nlm.nih.gov/pubmed/34462306 http://dx.doi.org/10.1523/JNEUROSCI.2534-20.2021

Ejemplares similares

Inferring mammalian tissue-specific regulatory conservation by predicting tissue-specific differences in open chromatin
por: Kaplow, Irene M., et al.
Publicado: (2022)

Machine learning sequence prioritization for cell type-specific enhancer design
por: Lawler, Alyssa J, et al.
Publicado: (2022)

The neurobiology of addiction
por: Uhl, George R., et al.
Publicado: (2019)

Neurobiology of addiction /
por: Koob, George F.
Publicado: (2006)

The Neurobiology of Cocaine Addiction
por: Nestler, Eric J.
Publicado: (2005)

The Neurobiology of Addiction: An Overview
por: Roberts, Amanda J., et al.
Publicado: (1997)

Neurobiology of addictions : implications for clinical practice

Addiction neurobiology : ethical and social implications
Publicado: (2009)

The emerging neurobiology of calorie addiction
por: García-Cáceres, Cristina, et al.
Publicado: (2014)

Glial Cells and the Neurobiology of Addiction
por: Lawrence, Diane M. P., et al.
Publicado: (2007)

Nicotine Addiction: Neurobiology and Mechanism
por: Tiwari, Raj Kumar, et al.
Publicado: (2020)

Editorial: Neurobiology of food addiction
por: Lampert, Carine, et al.
Publicado: (2023)

Editorial: Neurobiological Perspectives in Behavioral Addiction
por: Choi, Jung-Seok, et al.
Publicado: (2019)

Introduction. The neurobiology of drug addiction: new vistas
por: Robbins, T.W, et al.
Publicado: (2008)

Immune Function Genes, Genetics, and the Neurobiology of Addiction
por: Crews, Fulton T.
Publicado: (2012)

Neurobiology of opioid dependence in creating addiction vulnerability
por: Evans, Christopher J., et al.
Publicado: (2016)

Pathways Relating the Neurobiology of Attachment to Drug Addiction
por: Strathearn, Lane, et al.
Publicado: (2019)

Neurobiological Risk Factors for the Development of Internet Addiction in Adolescents
por: Tereshchenko, Sergey, et al.
Publicado: (2019)

Understanding the genetics and neurobiological pathways behind addiction (Review)
por: Popescu, Alexandra, et al.
Publicado: (2021)

Is there a shared neurobiology between aggression and Internet addiction disorder?
por: Hahn, Changtae, et al.
Publicado: (2014)

Neurobiology of Propofol Addiction and Supportive Evidence: What Is the New Development?
por: Xiong, Ming, et al.
Publicado: (2018)

Exercise-Based Interventions for Internet Addiction: Neurobiological and Neuropsychological Evidence
por: Li, Shanshan, et al.
Publicado: (2020)

Integrative multi-dimensional characterization of striatal projection neuron heterogeneity in adult brain
por: Gayden, Jenesis, et al.
Publicado: (2023)

Multifactorial Etiology of Adolescent Nicotine Addiction: A Review of the Neurobiology of Nicotine Addiction and Its Implications for Smoking Cessation Pharmacotherapy
por: Mahajan, Supriya D., et al.
Publicado: (2021)

The functional sequelae of schizophrenia: consequences of long-term pharmacotherapy and the neurobiology of addiction
por: Falkai, P., et al.
Publicado: (2011)

The neurobiology of addiction: the perspective from magnetic resonance imaging present and future
por: Suckling, John, et al.
Publicado: (2016)

Molecular rhythm alterations in prefrontal cortex and nucleus accumbens associated with opioid use disorder
por: Xue, Xiangning, et al.
Publicado: (2022)

Genesis of the Heroin-Induced Addictive Process: Articulation Between Psychodynamic and Neurobiological Theories
por: Scarna, Hélène
Publicado: (2020)

Editorial: Neurobiological Biomarkers for Developing Novel Treatments of Substance and Non-substance Addiction
por: Liu, Yi, et al.
Publicado: (2021)

Saudi addiction therapeutic communities:: Are they implementing the essential elements of addiction therapeutic communities?
por: Alshomrani, Abdulaziz T.
Publicado: (2016)

Reward Deficiency Syndrome (RDS): A Cytoarchitectural Common Neurobiological Trait of All Addictions
por: Blum, Kenneth, et al.
Publicado: (2021)

Current Perspectives on the Neurobiology of Drug Addiction: A Focus on Genetics and Factors Regulating Gene Expression
por: Duncan, Jhodie R.
Publicado: (2012)

The neurobiology of subjective tolerability to antipsychotic medications in Schizophrenia - is it also relevant to the genesis of comorbid addiction?
por: Awad, George
Publicado: (2010)

Highly impulsive rats: modelling an endophenotype to determine the neurobiological, genetic and environmental mechanisms of addiction
por: Jupp, Bianca, et al.
Publicado: (2013)

Is smartphone addiction really an addiction?
por: Panova, Tayana, et al.
Publicado: (2018)

Differences in addictive beliefs in people with psychostimulant addiction and in opioid addicts
por: Yan, Y., et al.
Publicado: (2022)

Study protocol: evaluation of the addictive potential of e-cigarettes (EVAPE): neurobiological, sociological, and epidemiological perspectives
por: Vollstädt-Klein, Sabine, et al.
Publicado: (2021)

Beyond Substance Addiction: Broadening the Concept of Addiction to Include Behavioral Addiction
por: Kim, Ji Hyun, et al.
Publicado: (2013)

Cell Type-Specific Oxidative Stress Genomic Signatures in the Globus Pallidus of Dopamine-Depleted Mice
por: Lawler, Alyssa J., et al.
Publicado: (2020)

Delineating the Psychic Structure of Substance Use and Addictions, from Neurobiology to Clinical Implications: Ten Years Later
por: Pani, Pier Paolo, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_a709070l8v6v97v5u7ilsv4d66