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Runt-Related Transcription Factor 3 Promotes Acute Myeloid Leukemia Progression

Acute myeloid leukemia (AML) is an aggressive hematological malignancy with high relapse/refractory rate. Genetic and epigenetic abnormalities are driving factors for leukemogenesis. RUNX1 and RUNX2 from the Runt-related transcription factor (RUNX) family played important roles in AML pathogenesis....

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Detalles Bibliográficos
Autores principales: Zhang, Wenwen, Ma, Qian, Long, Bing, Sun, Zhangyi, Liu, Lingling, Lin, Dongjun, Zhao, Minyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549545/
https://www.ncbi.nlm.nih.gov/pubmed/34722267
http://dx.doi.org/10.3389/fonc.2021.725336