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Synthesis of New Binary Thiazole-Based Heterocycles and Their Molecular Docking Study as COVID-19 Main Protease (M(pro)) Inhibitors

Isolated polynuclear binary heterocyclic compounds containing thiazole building block combined with benzofuran, pyrrole, thiazole, or thiophene via carboxamide and/or secondary amine as a junction are presented. The synthetic strategy of those is based on utilization of 2-chloroacetamido-4-phenylthi...

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Detalles Bibliográficos
Autores principales: Abdel-Latif, E., Khatab, T. K., Fekri, A., Khalifa, M. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pleiades Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549589/
https://www.ncbi.nlm.nih.gov/pubmed/34720568
http://dx.doi.org/10.1134/S1070363221090231