Siglec-8 Signals Through a Non-Canonical Pathway to Cause Human Eosinophil Death In Vitro

Sialic acid-binding immunoglobulin-like lectin (Siglec)-8 is a glycan-binding receptor bearing immunoreceptor tyrosine-based inhibitory and switch motifs (ITIM and ITSM, respectively) that is selectively expressed on eosinophils, mast cells, and, to a lesser extent, basophils. Previous work has show...

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Detalles Bibliográficos
Autores principales: Carroll, Daniela J., Cao, Yun, Bochner, Bruce S., O’Sullivan, Jeremy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549629/
https://www.ncbi.nlm.nih.gov/pubmed/34721399
http://dx.doi.org/10.3389/fimmu.2021.737988

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549629/
https://www.ncbi.nlm.nih.gov/pubmed/34721399
http://dx.doi.org/10.3389/fimmu.2021.737988

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