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Siglec-8 Signals Through a Non-Canonical Pathway to Cause Human Eosinophil Death In Vitro
Sialic acid-binding immunoglobulin-like lectin (Siglec)-8 is a glycan-binding receptor bearing immunoreceptor tyrosine-based inhibitory and switch motifs (ITIM and ITSM, respectively) that is selectively expressed on eosinophils, mast cells, and, to a lesser extent, basophils. Previous work has show...
Autores principales: | Carroll, Daniela J., Cao, Yun, Bochner, Bruce S., O’Sullivan, Jeremy A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549629/ https://www.ncbi.nlm.nih.gov/pubmed/34721399 http://dx.doi.org/10.3389/fimmu.2021.737988 |
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