Cargando…

Recent developments in chemical conjugation strategies targeting native amino acids in proteins and their applications in antibody–drug conjugates

Many fields in chemical biology and synthetic biology require effective bioconjugation methods to achieve their desired functions and activities. Among such biomolecule conjugates, antibody–drug conjugates (ADCs) need a linker that provides a stable linkage between cytotoxic drugs and antibodies, wh...

Descripción completa

Detalles Bibliográficos
Autores principales: Kang, Min Sun, Kong, Theresa Wai See, Khoo, Joycelyn Yi Xin, Loh, Teck-Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549674/
https://www.ncbi.nlm.nih.gov/pubmed/34760149
http://dx.doi.org/10.1039/d1sc02973h