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Recent developments in chemical conjugation strategies targeting native amino acids in proteins and their applications in antibody–drug conjugates
Many fields in chemical biology and synthetic biology require effective bioconjugation methods to achieve their desired functions and activities. Among such biomolecule conjugates, antibody–drug conjugates (ADCs) need a linker that provides a stable linkage between cytotoxic drugs and antibodies, wh...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549674/ https://www.ncbi.nlm.nih.gov/pubmed/34760149 http://dx.doi.org/10.1039/d1sc02973h |