Cargando…
Recent developments in chemical conjugation strategies targeting native amino acids in proteins and their applications in antibody–drug conjugates
Many fields in chemical biology and synthetic biology require effective bioconjugation methods to achieve their desired functions and activities. Among such biomolecule conjugates, antibody–drug conjugates (ADCs) need a linker that provides a stable linkage between cytotoxic drugs and antibodies, wh...
Autores principales: | Kang, Min Sun, Kong, Theresa Wai See, Khoo, Joycelyn Yi Xin, Loh, Teck-Peng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549674/ https://www.ncbi.nlm.nih.gov/pubmed/34760149 http://dx.doi.org/10.1039/d1sc02973h |
Ejemplares similares
-
Incorporation of native antibodies and Fc-fusion proteins on DNA nanostructures via a modular conjugation strategy
por: Rosier, Bas J. H. M., et al.
Publicado: (2017) -
Modular Synthesis of Trifunctional Peptide-oligonucleotide Conjugates via Native Chemical Ligation
por: Dastpeyman, Mohadeseh, et al.
Publicado: (2021) -
Chemical Conjugation in Drug Delivery Systems
por: Eras, Alexis, et al.
Publicado: (2022) -
Site-selective lysine conjugation methods and applications towards antibody–drug conjugates
por: Haque, Muhammed, et al.
Publicado: (2021) -
Antibody-drug conjugates: recent advances in conjugation and linker chemistries
por: Tsuchikama, Kyoji, et al.
Publicado: (2016)