Transcriptional Regulation of the Human IL5RA Gene through Alternative Promoter Usage during Eosinophil Development

Regulation of the IL-5 receptor alpha (IL5RA) gene is complicated, with two known promoters (P1 and P2) driving transcription, and two known isoforms (transmembrane and soluble) dichotomously affecting the signaling potential of the protein products. Here, we sought to determine the patterns of P1 a...

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Detalles Bibliográficos
Autores principales: Laffey, Kimberly G., Du, Jian, Schrum, Adam G., Ackerman, Steven J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549700/
https://www.ncbi.nlm.nih.gov/pubmed/34638583
http://dx.doi.org/10.3390/ijms221910245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549700/
https://www.ncbi.nlm.nih.gov/pubmed/34638583
http://dx.doi.org/10.3390/ijms221910245

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